Clinical Trial · NCT04296149

Beta- Probe and Surgery in GEP NET: Evaluation of a New Probe

Overview

Radioguided surgery (RGS) with beta- radioisotopes is a novel approach focused on developing a new probe which, detecting electrons and operating with low background, provides a clearer delineation of the margins of lesions with low radiation exposition for surgeons. To validate this procedure, ex vivo specimens of tumours expressing somatostatin receptors, as small-intestine neuroendocrine (SI-NET), will be tested

Sponsor

European Institute of Oncology

Phase

Phase 2

ClinicalTrials.gov

NCT04296149

Drug / Compound

DOTATOC

Isotope(s):

Target(s):

SSTR2

Ligand Class: Peptides

Chelator: DOTA

DOTATOC

Isotope(s):

Target(s):

SSTR2

Ligand Class: Peptides

Chelator: DOTA

Eligibility

Inclusion

* SI NET patients, Ga-68-DOTATOC PET/CT positive, proposed for surgery

Exclusion

* negative PET/CT; pregnancy