Clinical Trial · NCT05001204

68Ga-NOTA-RM26 PET/CT for the Detection of Gastrointestinal Stromal Tumor

Overview

This is an open-label positron emission tomography/computed tomography (PET/CT) study to investigate the diagnostic performance and evaluation efficacy of 68Ga-NOTA-RM26 in Gastrointestinal stromal tumor(GIST)patients. A single dose of 55.5 to 148 MBq(1.5-4 mCi) of 68Ga-NOTA-RM26 will be injected intravenously. Patients underwent whole-body PET/CT scans at 30-90 minutes after intravenous injection.

Phase

Early Phase 1

Contacts

Zhaohui Zhu, MD (CONTACT)

13611093752@163.com

13611093752

Rongxi Wang (CONTACT)

pumch_jacobwong@163.com

+8619800370331

ClinicalTrials.gov

NCT05001204

Drug / Compound

RM26

Isotope(s):
Target(s):
  • GRPR
Ligand Class: Peptides
Chelator: NOTA
Linker: PEG3

Eligibility

Inclusion

Inclusion criteria not yet provided.

Exclusion

  • The exclusion criteria included claustrophobia, pregnancy, breastfeeding, kidney or liver failure, inability to fulfill the study, and undergoing any preceding local or systemic therapies that might interfere with GRPR binding.