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Clinical Trial · NCT02174679
68Ga DOTATATE PET/CT in Neuroendocrine Tumors (Expanded Access)
Overview
To evaluate 68Ga-DOTATATE PET/CT for staging of patients with carcinoid, neuroendocrine tumors, medullary thyroid cancer and other cancers expressing somatostatin receptors.
Sponsor
Jonsson Comprehensive Cancer Center (UCLA)
Contacts
Johannes Czernin, MD (PRINCIPAL_INVESTIGATOR)
ClinicalTrials.gov
NCT02174679Drug / Compound
DOTATATE
Isotope(s):
GALLIUM-68
Radioisotope: Ga-68
Theranostic Role: PET Imaging
T1/2 (Half-Life): 68 minutes
Decay Mode: POSITRON β+ (88.9%), GAMMA, ELECTRON CAPTURE (8.7%)
Energy: Beta: max 1.9 MeV Gamma 1.1 MeV, 511 keV
Range: N/A
Decay Daughters: Zn68 (Stable)
Status: FDA Approvals: NETSPOT® (2016), LOCAMETZ® (2022), ILLUCIX® (2021)
Target(s):
- SSTR2
Ligand Class: Peptides
Chelator: DOTA
Eligibility
Inclusion
- Older than 18 years the time of radiotracer administration
- Able to remain still for duration of each imaging procedure (about 30 minutes)
Exclusion
- Any additional medical condition, serious concurrent illness, or other extenuating circumstance that, in the opinion of the Investigator, may significantly interfere with study compliance.
- Pregnant or nursing
- Inability to complete the needed investigational and standard-of-care imaging examinations due to other reasons (severe claustrophobia, radiation phobia, etc.)
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