Clinical Trial · NCT06419361

[68Ga]Ga-Sa-DABI-4 PET Imaging of Stimulator of Interferon Gene Expression in Cancer Patients

Overview

Stimulator of interferon gene (STING) protein plays a vital role in the immune surveillance of tumor microenvironment. Monitoring STING expression in tumors benefits the relevant STING therapy. This study will investigate the safety, biodistribution and potential usefulness of a novel 68Ga-labeled agonist (\[68Ga\]Ga-Sa-DABI-4) for noninvasive positron emission tomography (PET) imaging of STING expression in the tumor microenvironment.

Sponsor

First Affiliated Hospital of Chongqing Medical University

Phase

Early Phase 1

Contacts

Xiaoyang Zhang, PhD (CONTACT)

zhangxy@mail.bnu.edu.cn

023-89011755

ClinicalTrials.gov

NCT06419361

Drug / Compound

Sa-DABI-4

Isotope(s):

Target(s):

Stimulator of Interferon Genes

Ligand Class: Small Molecules

Eligibility

Inclusion

Patients with suspected or newly diagnosed or previously malignant disease.

Exclusion

Exclusion criteria not yet provided.