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Clinical Trial · NCT07215182
[68Ga]Ga-FAPI PET/CT for Response Evaluation During Immune Checkpoint Inhibitor Therapy in Malignant Melanoma
Overview
The goal of this clinical trial is to investigate the use of the tracer [68Ga]Ga-FAPI-46 for PET/CT-imaging in response evaluation of patients with advanced stage malignant melanoma treated with immune checkpoint inhibitor therapy (ICT).
Sponsor
Barbara Malene Fischer
Phase
Phase 2
Contacts
Inge Marie Svane, Professor, MD, PhD (Professor)
inge.marie.svane@regionh.dk
+4538683868
Marie MK Stolberg, MD
marie.manon.krebs.krarup@regionh.dk
+4535454416
ClinicalTrials.gov
NCT07215182Drug / Compound
Ga-FAPI-46
Isotope(s):
GALLIUM-68
Radioisotope: Ga-68
Theranostic Role: PET Imaging
T1/2 (Half-Life): 68 minutes
Decay Mode: POSITRON β+ (88.9%), GAMMA, ELECTRON CAPTURE (8.7%)
Energy: Beta: max 1.9 MeV Gamma 1.1 MeV, 511 keV
Range: N/A
Decay Daughters: Zn68 (Stable)
Status: FDA Approvals: NETSPOT® (2016), LOCAMETZ® (2022), ILLUCIX® (2021)
Target(s):
- FAP
Chelator: DOTA
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