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Clinical Trial · NCT03784625
Targeted Radionuclide Therapy for Metastatic Melanoma [131I] ICF01012: Phase I Study
Overview
This study is a phase I clinical trial aimed to determine the recommended dose of [131I]ICF01012 to administer for the treatment of patients with pigmented metastatic melanoma (binding [131I]ICF01012 ). The [131I]ICF01012 is a targeted radionuclide therapy with a high affinity for melanin.
Sponsor
Centre Jean Perrin
Phase
Early Phase 1
Contacts
Florent CACHIN, Pr (Principal Investigator)
florent.cachin@clermont.unicancer.fr
33473278089
ClinicalTrials.gov
NCT03784625Drug / Compound
Isotope(s):
IODINE-131
Radioisotope: I-131
Theranostic Role: Therapeutic Agent & SPECT Imaging
T1/2 (Half-Life): 8 Days
Decay Mode: BETA, GAMMA
Energy: βeta max 0.6 MeV Gamma 364 keV
Range: In Tissue: 0.8 -2.1 mm
Decay Daughters: Xe131
Status: FDA Approval: 1951-First FDA Approved Radiopharmaceutical), AZEDRA® (2018)
Target(s):
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