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Clinical Trial · NCT03033485
18F-Labeled Picolinamide PET Imaging of Melanoma Diagnosis
Overview
The purpose of this study is to assess the dosimetric properties of the positron emission tomography (PET) imaging probe 18F labeled Picolinamide (18F-P3BZA) and preliminarily evaluate its diagnosis value in melanoma patients.
Sponsor
Xijing Hospital
Phase
N/A
Contacts
Xiaowei Ma, M.D (CONTACT)
mxw_cn@hotmail.com
86-29-84771048
Jing Wang, M.D, Ph.D (CONTACT)
wangjing@fmmu.edu.cn
86-29-84775449
ClinicalTrials.gov
NCT03033485Drug / Compound
FDG
Isotope(s):
FLUORINE-18
Radioisotope: F-18
Theranostic Role: PET Imaging
T1/2 (Half-Life): 1.8 Hours
Decay Mode: POSITRON β+ (96.7%), ELECTRON CAPTURE (3.3%), GAMMA 511 keV
Energy: Eβ+ 635 keV
Range: N/A
Decay Daughters: O18 (Stable)
Status: FDA Approvals: FDG (Cancer 2005): GLUDEF®, METATRACE® AXUMIN® (2016), PYLARIFY® (2023), POSLUMA® (2024)
Target(s):
- Glucose Transport
Ligand Class: Small Molecules
P3BZA
Isotope(s):
FLUORINE-18
Radioisotope: F-18
Theranostic Role: PET Imaging
T1/2 (Half-Life): 1.8 Hours
Decay Mode: POSITRON β+ (96.7%), ELECTRON CAPTURE (3.3%), GAMMA 511 keV
Energy: Eβ+ 635 keV
Range: N/A
Decay Daughters: O18 (Stable)
Status: FDA Approvals: FDG (Cancer 2005): GLUDEF®, METATRACE® AXUMIN® (2016), PYLARIFY® (2023), POSLUMA® (2024)
Target(s):
- MC1R
Ligand Class: Small Molecules
Eligibility
Inclusion
- * patients with melanoma: diagnosed by pathology and ready for surgery
Exclusion
- pregnant women
- * patients with melanoma: refuse or cannot endure surgery
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