Clinical Trial · NCT07599917

Diagnostic Performance and Quantitative Analysis of [18F]FET PET in Brain Tumours

Overview

This is a retrospective study encompassing all \[18F\]FET PET scans performed at our centre. By analysing both static and dynamic scans, conducting in-depth kinetic modelling, and comparing quantitative parameters across different tumour types and clinical contexts, the study aims to determine the true diagnostic value of \[18F\]FET PET in everyday clinical practice. The ultimate goal is to identify imaging biomarkers useful for improving tumour characterisation and distinguishing recurrence from post-treatment changes, thereby strengthening the role of \[18F\]FET PET in modern neuro-oncology.

Sponsor

IRCCS San Raffaele

Contacts

Chiara Catalano, PhD (CONTACT)

catalano.chiara@hsr.it

+39 0226433639

Alexandra Lazar, Dr. (CONTACT)

lazar.alexandra@hsr.it

ClinicalTrials.gov

NCT07599917

Drug / Compound

FET

Isotope(s):

Target(s):

Amino Acid Transport

Ligand Class: Small Molecules

Eligibility

Inclusion

Patients who underwent a brain PET/CT or PET/MRI scan with \[18F\]FET for clinical reasons during the study period.
Availability of the corresponding static and dynamic images.

Exclusion

. Pregnancy or breastfeeding