Clinical Trial · NCT02631655

POSitron Emission Imaging Using 18F-FDOPA in Neurooncology

Overview

18F-FDOPA PET is expensive. It is mandatory therefore to assess its impact on the management of patients with high-grade gliomas in order to provide medico-economic justification for its use. The article by the UCLA group showed that 18F-FDOPA modified 41% of management decisions for patients with brain tumors (Walter JNM 2012). However, this study comprised 58 patients, combined primary and recurring tumors, and was based on questionnaires sent out to referring physicians. A targeted study is needed, therefore, to make a prospective multicenter assessment of the contribution of this technique in the context of high-grade glial tumors and neurooncology MCCs.

Sponsor

Centre Antoine Lacassagne

Phase

N/A

Contacts

Jacques DARCOURT, PHD (STUDY_DIRECTOR)

ClinicalTrials.gov

NCT02631655

Drug / Compound

FDOPA

Isotope(s):
Target(s):
  • LAT1/LAT2
Ligand Class: Small Molecules

Eligibility

Inclusion

  • Patient diagnosed with high-grade glioma

Exclusion

Exclusion criteria not yet provided.