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Clinical Trial · NCT07007325
Prospective Feasibility Pilot Study Evaluating the Value of [68Ga]Ga-PENTIXAFOR PET-CT in Patients With Metastatic Small Cell Lung Cancer (SCLC) at Diagnosis and Disease Progression
Overview
[68Ga]Ga-PentixaFor PET-CT will be performed in patients with Small cell lung cancer (SCLC) to confirm the targeting of CXCR4 by [68Ga]Ga-PentixaFor
Sponsor
Institut Cancerologie de l'Ouest
Phase
Early Phase 1
Contacts
Marie LACOMBE, MD
marie.lacombe@ico.unicancer.fr
+33 241352700
Nadia ALLAM, PhD
nadia.allam@ico.unicancer.fr
+33 2 40 67 98 26
ClinicalTrials.gov
NCT07007325Drug / Compound
[68Ga]Ga-PENTIXAFOR
Isotope(s):
GALLIUM-68
Radioisotope: Ga-68
Theranostic Role: PET Imaging
T1/2 (Half-Life): 68 minutes
Decay Mode: POSITRON β+ (88.9%), GAMMA, ELECTRON CAPTURE (8.7%)
Energy: Beta: max 1.9 MeV Gamma 1.1 MeV, 511 keV
Range: N/A
Decay Daughters: Zn68 (Stable)
Status: FDA Approvals: NETSPOT® (2016), LOCAMETZ® (2022), ILLUCIX® (2021)
Target(s):
- CXCR4
Ligand Class: Peptides
Chelator: DOTA
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