Clinical Trial · NCT04833959

Pilot Study of 89-Zr Panitumumab in Pancreas Cancer

Overview

The main purpose of the study is to assess the safety of 89Zr-panitumumab as a molecular imaging agent in patients with (metastatic) pancreas cancer.

Sponsor

Stanford University

Phase

Phase 1

Contacts

Andrei Iagaru (PRINCIPAL_INVESTIGATOR)

ClinicalTrials.gov

NCT04833959

Eligibility

Inclusion

  • Confirmed diagnosis of pancreatic cancer.

Exclusion

  • Known hypersensitivity to deferoxamine or any of its components.
  • Pregnant or breastfeeding.
  • History of infusion reactions to monoclonal antibody therapies.
  • Subjects with a history or evidence of interstitial pneumonitis or pulmonary fibrosis.
  • Myocardial infarction (MI); cerebrovascular accident (CVA); uncontrolled congestive heart failure (CHF); significant liver disease; or unstable angina within 6 months prior to enrollment.
  • Severe renal disease or anuria.
  • Subjects receiving Class IA (quinidine, procainamide) or Class III (dofetilide, amiodarone, sotalol) antiarrhythmic agents.