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Clinical Trial · NCT06607692
Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed).
Overview
Study in children and adolescents of 177Lu DOTATATE (Lutathera®) combined with the PARP inhibitor olaparib for treatment of recurrent or relapsed solid tumours expressing somatostatin receptors (SSTR) (LuPARPed)
Sponsor
Fundación de investigación HM
Phase
Phase 1/2
Contacts
Marta Osuna Marco MD, Medical Degree (CONTACT)
marta.osuna@startmadrid.com
+34 917 08 99 35
Marta Osuna Marco, PhD (STUDY_DIRECTOR)
START Pediatrics (CONTACT)
pediatrics@startresearch.com
ClinicalTrials.gov
NCT06607692Eligibility
Inclusion
- Score = 1: Above blood pool and lower than liver
- Score = 0: Below or equal to blood pool
- ≥ 3 years at the moment of inclusion in the trial.
- Diagnosis: relapsed/refractory solid tumours with positive uptake on SSTR-PET (PET-CT or PET-MRI), performed in the previous three months before entering the study.The evaluation of SSTR expression will be classified according to a qualitative 4-point scale: SSTR expression V (visual score):
- * 18 months - 18 years of age at the time of the initial diagnosis.
Exclusion
Exclusion criteria not yet provided.
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