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Clinical Trial · NCT07025512
177Lu-PSMA-617 in Metastatic Castration Resistant Prostate Cancer (mCRPC) With Bone Marrow Involvement and Cytopenia
Overview
To control mCRPC that has spread to the bone marrow. The safety and effects of this treatment will also be studied.
Sponsor
MD Anderson Cancer Center
Phase
Phase 2
Contacts
Bagi Jana, MD
bjana@mdanderson.org
713-563-0670
ClinicalTrials.gov
NCT07025512Drug / Compound
177Lu-PSMA-617
Isotope(s):
LUTETIUM-177
Radioisotope: Lu-177
Theranostic Role: Therapeutic Agent & SPECT Imaging
T1/2 (Half-Life): 6.7 Days
Decay Mode: BETA, GAMMA
Energy: Eβeta max 497 keV, Gamma 113-208 keV
Range: In Tissue: 0.25-2mm
Decay Daughters: Hf177
Status: FDA Approvals: PLUVICTO® (2022), LUTATHERA® (2017)
Target(s):
- PSMA
Ligand Class: Small Molecules
Chelator: DOTA
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