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Clinical Trial · NCT05134064
68Ga-PSMA PET/CT Imaging in Assessment of Prostate Cancer
Overview
Dual-time point 68Ga-PSMA PET/CT could increase the lesion detection in PCa patients, it remains difficult to perform in clinical practice. The possibility of one-time point 68Ga-PSMA PET/CT imaging could be achieved using a total-body PET/CT.
Sponsor
RenJi Hospital
ClinicalTrials.gov
NCT05134064Drug / Compound
PSMA
Isotope(s):
GALLIUM-68
Radioisotope: Ga-68
Theranostic Role: PET Imaging
T1/2 (Half-Life): 68 minutes
Decay Mode: POSITRON β+ (88.9%), GAMMA, ELECTRON CAPTURE (8.7%)
Energy: Beta: max 1.9 MeV Gamma 1.1 MeV, 511 keV
Range: N/A
Decay Daughters: Zn68 (Stable)
Status: FDA Approvals: NETSPOT® (2016), LOCAMETZ® (2022), ILLUCIX® (2021)
Target(s):
- PSMA
Ligand Class: Small Molecules
Eligibility
Inclusion
- positive 68Ga-PSMA findings
- primary staging of pathology-confirmed PCa or evidence of BCR with PSA value \> 0.2 ng/ml
- both standard and delayed scans were performed on the total-body PET/CT
Exclusion
- only one scan was performed
- negative PSMA results
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