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Clinical Trial · NCT03164837
68Ga-NOTA-RM26 PET/CT in Prostate Cancer Patients
Overview
This is an open-label positron emission tomography/computed tomography (PET/CT) study to investigate the diagnostic performance and evaluation efficacy of 68Ga-NOTA-RM26 in prostate cancer patients. A single dose of 111-148 Mega-Becquerel (MBq) 68Ga-NOTA-RM26 will be injected intravenously. Visual and semiquantitative method will be used to assess the PET/CT images.
Phase
Phase 1
Contacts
Jingjing Zhang, M.D.,PhD. (CONTACT)
zhangjingjingtag@163.com
+86 10 69154196
Zhaohui Zhu, M.D.,PhD. (STUDY_CHAIR)
ClinicalTrials.gov
NCT03164837Drug / Compound
RM26
Isotope(s):
GALLIUM-68
Radioisotope: Ga-68
Theranostic Role: PET Imaging
T1/2 (Half-Life): 68 minutes
Decay Mode: POSITRON β+ (88.9%), GAMMA, ELECTRON CAPTURE (8.7%)
Energy: Beta: max 1.9 MeV Gamma 1.1 MeV, 511 keV
Range: N/A
Decay Daughters: Zn68 (Stable)
Status: FDA Approvals: NETSPOT® (2016), LOCAMETZ® (2022), ILLUCIX® (2021)
Target(s):
- GRPR
Ligand Class: Peptides
Chelator: NOTA
Linker: PEG3
Eligibility
Inclusion
Inclusion criteria not yet provided.
Exclusion
- The exclusion criteria included claustrophobia, kidney or liver failure, and inability to fulfill the study.
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