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Clinical Trial · NCT07523607
FAP PET/CT for Staging Patients With Breast Cancer
Overview
This study aims to evaluate the clinical utility of \[68Ga\]Ga-FAP-2268 PET/CT for disease staging and assessment in patients with high-risk primary breast cancer. By targeting fibroblast activation protein (FAP), this novel imaging approach may offer improved tumor visualization compared to conventional imaging, which may help improve treatment planning.
Sponsor
Odense University Hospital
Phase
Phase 2
Contacts
Sara E Dahlsgaard-Wallenius, MD (CONTACT)
sara.elisabeth.wallenius@rsyd.dk
+45 53 57 45 55
ClinicalTrials.gov
NCT07523607Drug / Compound
FAP-2286
Isotope(s):
GALLIUM-68
Radioisotope: Ga-68
Theranostic Role: PET Imaging
T1/2 (Half-Life): 68 minutes
Decay Mode: POSITRON β+ (88.9%), GAMMA, ELECTRON CAPTURE (8.7%)
Energy: Beta: max 1.9 MeV Gamma 1.1 MeV, 511 keV
Range: N/A
Decay Daughters: Zn68 (Stable)
Status: FDA Approvals: NETSPOT® (2016), LOCAMETZ® (2022), ILLUCIX® (2021)
Target(s):
- FAP
Ligand Class: Peptides
Chelator: DOTA
Eligibility
Inclusion
- Biopsy-verified newly diagnosed breast cancer
Exclusion
Exclusion criteria not yet provided.
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