Clinical Trial · NCT01492192

RGD-PET-CT in Cancer Angiogenesis

Overview

The goal of this clinical research study is to look at 2 new methods of scanning and see whether they can help researchers predict which tumours will respond to drugs that attack tumour blood supply.

Sponsor

University Hospital, Grenoble

Phase

Phase 2

Contacts

Fergus Gleeson (PRINCIPAL_INVESTIGATOR)

ClinicalTrials.gov

NCT01492192

Eligibility

Inclusion

  • Standard staging CT scan performed within 28 days of first research scan
  • Patient is not lactating or pregnant
  • Patients considered suitable for therapy with TKI for RCC according to responsible clinician
  • Patient is able to tolerate and comply with scanning procedure
  • Patients should have advanced or metastatic RCC confirmed by histological diagnosis
  • Absence of any psychological, familial, sociological or geographical condition which in the opinion of the Investigator may potentially hamper compliance with the study protocol and follow-up schedule; those conditions should be discussed with the patient before registration in the trial
  • Adequate renal function (creatinine \<1.25xULN)
  • The patient has not received chemotherapy, radiotherapy, surgery or any other treatment against cancer within 4 weeks prior to recruitment
  • Measurable tumour according to RECIST v1.1 criteria

Exclusion

  • Not applicable