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Clinical Trial · NCT00003102
Monoclonal Antibody Therapy in Treating Patients With Advanced Kidney Cancer
Overview
RATIONALE: Monoclonal antibodies can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. PURPOSE: Phase I/II trial to study the effectiveness of monoclonal antibody therapy in treating patients with advanced kidney cancer.
Sponsor
Olivia Newton-John Cancer Research Institute
Phase
Phase 1/2
Contacts
Chaitanya R. Divgi, MD (STUDY_CHAIR)
ClinicalTrials.gov
NCT00003102Drug / Compound
cG250
Isotope(s):
IODINE-131
Radioisotope: I-131
Theranostic Role: Therapeutic Agent & SPECT Imaging
T1/2 (Half-Life): 8 Days
Decay Mode: BETA, GAMMA
Energy: βeta max 0.6 MeV Gamma 364 keV
Range: In Tissue: 0.8 -2.1 mm
Decay Daughters: Xe131
Status: FDA Approval: 1951-First FDA Approved Radiopharmaceutical), AZEDRA® (2018)
Target(s):
- CAIX
Ligand Class: Antibodies
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