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Clinical Trial · NCT07444723
A Phase II Study of Accuracy of 18F-Fluorocholine PET/MRI and NeuroEXPLORER PET/CT Imaging for Localization of Parathyroid Tumors
Overview
This study investigates the efficacy of 18F-FCH PET/ MRI and PET/CT for localization of parathyroid tumors in primary hyperparathyroidism (sporadic or heritable forms and parathyroid cancer).
Sponsor
National Institute of Diabetes and Digestive and Kidney Diseases
Phase
Phase 2/3
Contacts
Smita Jha, M.D.
smita.jha@nih.gov
(301) 827-1930
Lynn M Bliss
lynn.bliss@nih.gov
(301) 435-7921
ClinicalTrials.gov
NCT07444723Drug / Compound
18F-Fluorocholine
Isotope(s):
FLUORINE-18
Radioisotope: F-18
Theranostic Role: PET Imaging
T1/2 (Half-Life): 1.8 Hours
Decay Mode: POSITRON β+ (96.7%), ELECTRON CAPTURE (3.3%), GAMMA 511 keV
Energy: Eβ+ 635 keV
Range: N/A
Decay Daughters: O18 (Stable)
Status: FDA Approvals: FDG (Cancer 2005): GLUDEF®, METATRACE® AXUMIN® (2016), PYLARIFY® (2023), POSLUMA® (2024)
Target(s):
- Phospholipid Metabolism
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