Clinical Trial · NCT00591643

Adrenal Scans With Radioiodine-Labeled Norcholesterol (NP-59)

Overview

The purpose of this study is to find out if your adrenal glands are normal or abnormal. This can be determined by whether or not your adrenal gland concentrates more of a labeled building block of adrenal hormone, norcholesterol. This labeled material had been used as an investigative diagnostic tool for imaging adrenal glands for many years with success in our hands. This is a diagnostic procedure. CT, MRI and Ultrasound can determine the size and presence or absence of tumor but cannot assess the function of the adrenal glands. To determine hormone concentrations from blood samples would involve more invasive catherization.

Sponsor

Memorial Sloan Kettering Cancer Center

Phase

Phase 1

Contacts

Neeta Pandit-Taskar, MD (PRINCIPAL_INVESTIGATOR)

ClinicalTrials.gov

NCT00591643

Drug / Compound

NP-59

Isotope(s):
Target(s):
  • Norcholesterol
Ligand Class: Small Molecules

Eligibility

Inclusion

  • Patient with clinical and laboratory suspicions of hypersecretion of adrenal cortical hormones

Exclusion

  • n/a