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Clinical Trial · NCT05392985
Detection and Analysis of MBC With Heterogeneous ER Expression
Overview
To investigate the treatment pattern and efficacy of MBC patients with ER heterogeneity using a novel convenient way of 18F-fluoroestradiol positron emission tomography/computed tomography (18F-FES PET/CT).
Sponsor
Fudan University
Contacts
Biyun Wang (PRINCIPAL_INVESTIGATOR)
ClinicalTrials.gov
NCT05392985Drug / Compound
fluoroestradiol
Isotope(s):
FLUORINE-18
Radioisotope: F-18
Theranostic Role: PET Imaging
T1/2 (Half-Life): 1.8 Hours
Decay Mode: POSITRON β+ (96.7%), ELECTRON CAPTURE (3.3%), GAMMA 511 keV
Energy: Eβ+ 635 keV
Range: N/A
Decay Daughters: O18 (Stable)
Status: FDA Approvals: FDG (Cancer 2005): GLUDEF®, METATRACE® AXUMIN® (2016), PYLARIFY® (2023), POSLUMA® (2024)
Target(s):
- Estrogen Receptor
Ligand Class: Small Molecules
Eligibility
Inclusion
- Patients received further treatment.
- Patients received 18F-FES PET/CT in Fudan University Shanghai Cancer Center from 2017-2021.
- Patients had both FES positive (FES+) and negative (FES-) lesions in FES exam.
Exclusion
Exclusion criteria not yet provided.
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