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Luke Nordquist, MD, FACP, CEO
drluke@xcancer.comTony Romero, MS, CCRC, Director of Research
tromero@gucancer.comExploring the Potential for 18F-fluoro-ethyl-tyrosine (18F-FET) to Enable Wider Access to Molecular Imaging for Patients With Pituitary Adenomas (FET-pit-PET Study)
Description:
The goal of this single centre pilot study is to explore whether 18F-fluoro-ethyl-tyrosine PET (FET-PET) yields comparable findings to 11C-methionine PET (Met-PET) for the localisation of pituitary tumours.
Sponsor:
University of Cambridge
Contacts:
James MacFarlanejm2267@medschl.cam.ac.uk
01223 250882
Government Study Link:
NCT06584123 - Click here to see study onClinicalTrials.gov
18F-fluoro-ethyl-tyrosine PET (FET-PET)
Isotope(s):
FLUORINE-18
Radioisotope: F-18
Theranostic Role: PET Imaging
T1/2 (Half-Life): 1.8 Hours
Decay Mode: POSITRON β+ (96.7%), ELECTRON CAPTURE (3.3%), GAMMA 511 keV
Energy: Eβ+ 635 keV
Range: N/A
Decay Daughters: O18 (Stable)
Status: FDA Approvals: FDG (Cancer 2005): GLUDEF®, METATRACE® AXUMIN® (2016), PYLARIFY® (2023), POSLUMA® (2024)
Target(s):
- Amino Acid Transport
11C-methionine PET (Met-PET)
Isotope(s):
CARBON-11
Radioisotope: C-11
Theranostic Role: PET Imaging, SPECT Imaging
T1/2 (Half-Life): 20.4 Min
Decay Mode: POSITRON β+ (99.8%), ELECTRON CAPTURE (0.2%), GAMMA
Energy: max 0.96 MeV, mean 386 keV, Gamma 511 keV
Range: N/A
Decay Daughters: B11 (Stable)
Status: FDA Approval: Carbon 11 Choline (2012)
Target(s):
- Amino Acid Transport
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