XCancer

Beta- Probe and Surgery in GEP NET: Evaluation of a New Probe

Description:

Radioguided surgery (RGS) with beta- radioisotopes is a novel approach focused on developing a new probe which, detecting electrons and operating with low background, provides a clearer delineation of the margins of lesions with low radiation exposition for surgeons. To validate this procedure, ex vivo specimens of tumours expressing somatostatin receptors, as small-intestine neuroendocrine (SI-NET), will be tested

Sponsor:

European Institute of Oncology

Phase:

Phase 2

Government Study Link:

NCT04296149 - Click here to see study on

ClinicalTrials.gov

DOTATOC

Isotope(s):
Target(s):
  • SSTR2
Ligand Class: Peptides
Chelator: DOTA

DOTATOC

Isotope(s):
Target(s):
  • SSTR2
Ligand Class: Peptides
Chelator: DOTA
Inclusion
  • * SI NET patients, Ga-68-DOTATOC PET/CT positive, proposed for surgery
Exclusion
  • * negative PET/CT; pregnancy