XCancer

[68Ga]Ga-Sa-DABI-4 PET Imaging of Stimulator of Interferon Gene Expression in Cancer Patients

Description:

Stimulator of interferon gene (STING) protein plays a vital role in the immune surveillance of tumor microenvironment. Monitoring STING expression in tumors benefits the relevant STING therapy. This study will investigate the safety, biodistribution and potential usefulness of a novel 68Ga-labeled agonist (\[68Ga\]Ga-Sa-DABI-4) for noninvasive positron emission tomography (PET) imaging of STING expression in the tumor microenvironment.

Sponsor:

First Affiliated Hospital of Chongqing Medical University

Phase:

Early Phase 1

Contacts:

Xiaoyang Zhang, PhD (CONTACT)

zhangxy@mail.bnu.edu.cn

023-89011755

Government Study Link:

NCT06419361 - Click here to see study on

ClinicalTrials.gov

Sa-DABI-4

Isotope(s):
Target(s):
  • Stimulator of Interferon Genes
Ligand Class: Small Molecules
Inclusion
  • Patients with suspected or newly diagnosed or previously malignant disease.
Exclusion

Exclusion Criteria Not Yet Provided