XCancer

Nectin-4 Specific LMW PET Probe Imaging in Urothelial Carcinoma

Description:

To evaluate the ability of \[68Ga\]N188 to detect nectin-4 overexpression in patients with urothelial carcinoma, especially in patients with recurrent or advanced bladder cancer.

Sponsor:

Peking University Cancer Hospital & Institute

Phase:

N/A

Contacts:

Zhi Yang, Professor (CONTACT)

pekyz@163.com

010-88196495

Hua Zhu, Professor (CONTACT)

zhuhuabch@pku.edu.cn

010-88196495

Government Study Link:

NCT05321316 - Click here to see study on

ClinicalTrials.gov

N188

Isotope(s):
Target(s):
  • Nectin-4
Ligand Class: Small Molecules

FDG

Isotope(s):
Target(s):
  • Glucose Transport
Ligand Class: Small Molecules
Inclusion
  • Good follow-up compliance;
  • Heart function is normal;
  • Normal heart function;
  • 1. 18-75 years old, male or female;
  • Estimated survival ≥12 weeks;
Exclusion
  • Pregnant patients;
  • 1. Serious abnormality of liver, kidney and blood;
  • Pregnant and lactation women;3\) unable to lie flat for half an hour; 4) Refuse to join the clinical investigator; 5) Suffering from claustrophobia or other mental diseases; 6) Other conditions that researchers deem unsuitable for participating in the experiment.