XCancer

Application of ⁶⁸Ga-FXX489 (NNS309) PET/CT Imaging in Diagnosis of Tumor Diseases.

Description:

A new radiotracer, 68Ga-FXX489 (NNS309), has been developed for tracking fibroblast activation protein (FAP) and visualizing the tumor stroma. The purpose of the study is to explore the diagnostic value of 68Ga-FXX489 (NNS309) PET/CT imaging in oncological diseases, to assess its safety, imaging characteristics, and biodistribution after administration.

Sponsor:

First Hospital of China Medical University

Phase:

Phase 1

Contacts:

Xuena Li (STUDY_DIRECTOR)

Xuena Li (CONTACT)

lixuenacmunm@163.com

0086-18040099351

Government Study Link:

NCT07144085 - Click here to see study on

ClinicalTrials.gov

FXX489

Isotope(s):
Target(s):
  • FAP
Ligand Class: Peptides
Chelator: DOTA

FAP-2286

Isotope(s):
Target(s):
  • FAP
Ligand Class: Peptides
Chelator: DOTA
Inclusion
  • Patients with a high suspicion of oncological diseases.
Exclusion
  • Severe cardiac dysfunction, cardiac function class III-IV.
  • Renal failure (serum creatinine level \> 1.2 mg/dl).
  • Severe visual or auditory impairment, cognitive disorders, or patients with claustrophobia who cannot communicate effectively.