XCancer

Positron Emission Tomograph(PET) Imaging Explores the Role of SF-DEVD-2 in Monitoring Tumor Efficacy

Description:

This is a single arm study to determining the value of apoptotic molecular probe SF-DEVD-2 in the early evaluation of tumor efficacy and comparing it head-to-head wihe 18F-FDG(18F-2-fluoro-2-deoxy-D-glucose)

Sponsor:

Affiliated Hospital of Jiangnan University

Phase:

Early Phase 1

Contacts:

Chunjing Yu (CONTACT)

ycj_wxd1978@163.com

15312238622

Chunjing Yu (PRINCIPAL_INVESTIGATOR)

Government Study Link:

NCT05828238 - Click here to see study on

ClinicalTrials.gov

SF-DEVD-2

Isotope(s):
Target(s):
  • Caspase-3
Ligand Class: Small Molecules

FDG

Isotope(s):
Target(s):
  • Glucose Transport
Ligand Class: Small Molecules
Inclusion
  • Age18-70, male or female;
  • Pathology is HER3+、triple negative patients
  • Diagnosed with stage 2 or 3 breast cancer
  • Solid tumors、masses larger than 2cm with lymph node metastasis
  • 1. Patients voluntarily signed informed consent;
Exclusion
  • Abnormal liver and kidney function (more than five times the normal value)
  • Diagnosis level of breast cancer stage 4 or second time tumor patients
  • 1. Age greater than or equal to 70 years old