Radioligand Efficacy Comparison by Initial PSA-Response Outcome in Metastatic CRPC With Lutetium 177Lu PSMA RLT (RECIPROCAL)

Description:

This randomized phase III trial examines whether lengthening the dosage interval in an adaptive manner for the prostate cancer drug lutetium 177 Lu PSMA RLT improves quality of life without decreasing lifespan when compared to the standard way this medication is given.

Sponsor:

Alliance for Clinical Trials in Oncology

Contacts:

Shiva Baghaie, MPH

guprotocols@alliancenctn.org

773-702-9171

177Lu-PSMA-617

Isotope(s):
Target(s):
  • PSMA
Ligand: Small Molecules
Chelator: DOTA
Linker: 2-naphthyl-L-alanine (Nal) and tranexamic acid (TXA)
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